WIPE, DISINFECTANT CAVIWIPES XLG SNGL 12X10 (50/BX. Monobutyl ether of ethylene glycol 6.0 --Monohexyl ether of ethylene glycol-- 6.0 BTC 2125 (50%) 0.9 0.9 Neodol 25-9 1.3 1.3 d-Limonene 0.4 0.4 Sodium metasilicate 1.0 1.0 Water qs to 100 Appearance Clear Cloudy % Carbon in glycol ether 61 65.75 NTP, ACGIH, or OSHA. [23] 2-Butoxyethanol biodegrades in soils and water, with a half life of 1–4 weeks in aquatic environments. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Medical Conditions Aggravated By Exposure: None currently known. Male rabbits showed a loss of coordination and equilibrium after exposure to 400 ppm of 2-butoxyethanol for two days. The course of ethylene glycol toxicity is classically divided into three broad overlapping categories of adverse health effects. Ethylene glycol is a “toxic alcohol”, meaning that although chemically it is similar to ethanol (the active component of alcoholic beverages), it is much more poisonous if 2-Butoxyethanol is an organic compound with the chemical formula BuOC2H4OH (Bu = CH3CH2CH2CH2). Ethylene Glycol Monobutyl Ether 1-5%; Diisobutylphenoxyethoxyethyl Dimethyl Benzyl Ammonium Chloride 0.28%; Key Features. TWA: 20 ppm 8 hour(s). 2-Butoxyethanol is commonly obtained through two processes; the ethoxylation reaction of butanol and ethylene oxide in the presence of a catalyst: or the etherification of butanol with 2-chloroethanol. Although there are alternatives to EGBE for individual applications, there is no across-the-board replacement. In use since the 1930s, glycol ethers are solvents that dissolve both water-soluble and hydrophobic substances. CaviCide is a convenient, ready-to-use, intermediate-level surface disinfectant that is effective against TB, HBV, HCV, viruses (hydrophilic and lipophilic), bacteria (including MRSA and VRE) and fungi. Studies suggest that there is little possibility of significant adverse health effects in humans exposed to EGBE at levels encountered in workplaces that comply with OSHA exposure limits. See all FAQs here. Web. Medical Conditions Aggravated By Exposure: Due to its defatting properties, isopropyl alcohol may aggravate an existing skin condition. Ethylene Glycol Monobutyl Ether (Glycol Ether) 111-76-2 1-5% Protection of Stratospheric Ozone: This product is not known to contain or to have been manufactured with ozone depleting substances as defined in 40 CFR Part 82, Appendix A to Subpart A. CERCLA SECTION 103: This product is not subject to CERCLA reporting requirements; however, many For more than 60 years, glycol ethers have been used as key ingredients in the production of cleaners, degreasers, water-based coatings, and solvent based coating systems. Packaging 1, 2.5 L in glass bottle [20] 2-butoxyethanol has not been shown to penetrate shale rock in a study conducted by Manz. Synonyms Ethylene Glycol Monobutyl Ether, Butyl Cellosolve* 8 ETHYLENE GLYCOL ETHERS, NTP TOXICITY REPORT NUMBER 26 Glycol alkyl ethers represent a class of high-production-volume chemicals with widespread industrial applications as solvents and chemical intermediates. Glycol Ether EB is a solvent used in a wide range of industries. Ethylene glycol (EG) is a colorless, odorless, bittersweet-tasting liquid that has many household and commercial uses. Department of Health and Human Services. As a result, some misperceptions developed in the use of EGBE. [9][12] Products that contain 2-butoxyethanol include acrylic resin formulations, asphalt release agents, firefighting foam, leather protectors, oil spill dispersants, degreaser applications, photographic strip solutions, whiteboard cleaners, liquid soaps, cosmetics, dry cleaning solutions, lacquers, varnishes, herbicides, latex paints, enamels, printing paste, and varnish removers, and silicone caulk. [26], Neurological effects have also been observed in animals exposed to 2-butoxyethanol. A U.S. Environmental Protection Agency review finds inhalation of 2 … [10] It is also used as a crude oil-water coupling solvent for more general oil well workovers. It is an excellent solvent for household and industrial cleaners, rust removers, and disinfectant. ETHYLENE GLYCOL MONOBUTYL ETHER; 2-butoxyethanol; butyl cellosolve 111-76-2 1 - 5 ACGIH TLV (United States). Ethylene glycol has a sweet taste and is often accidentally or intentionally ingested. World production is estimated to be 200 to 500 kt/a, of which 75% is for paints and coatings[9] and 18% for metal cleaners and household cleaners. This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol. Twitter! [10], 2-Butoxyethanol is a glycol ether with modest surfactant properties (and it can be used as a mutual solvent). C. 4. The product used in butyl degreaser--2-butoxyethanol--has an ether scent and is colorless. Twitter! Effects of Overexposure:SEE HEALTH HAZARDS. may cause headache, nausea, vomiting and weakness. OH. 31236; UNII: HIE492ZZ3T CompTox … It is a known respiratory irritant[3] and can be acutely toxic but animal studies did not find it to be mutagenic, and no studies suggest it is a human carcinogen. Diethylene glycol monoethyl ether (C8H16O4) an ethylene-series glycol ether. [22] It has not been identified as a major environmental contaminant, nor is it known to bio-accumulate. Blood or urine concentrations of 2-butoxyethanol or the metabolite 2-butoxyacetic acid may be measured using chromatographic techniques. CH. A biological exposure index of 200 mg 2-butoxyacetic acid per g creatinine has been established in an end-of-shift urine specimen for U.S. Follow CleanItSupply on Ethylene glycol monobutyl ether: The US National Toxicology Program (NTP) conducted a 2-year inhalation chronic toxicity and carcinogenicity study with ethylene glycol monobutyl ether in rats and mice. Glycol ethers are a group of solvents based on alkyl ethers of ethylene glycol or propylene glycol commonly used in paints and cleaners. By Olivia Harris, Sharon Wilbur, Julia George, and Carol Eisenmann. This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol. Diethylene glycol monobutyl ether (DEGBE) is used: • In the preparation of blocked isocyanate systems for coil coating, electro-coating and powder coating. 2-butoxyethanol (or ethylene glycol monobutyl ether) and other glycol ethers. It is the main ingredient of many home, commercial and industrial cleaning solutions. It is also approved by the U.S. FDA to be used as direct and indirect food additives, which include antimicrobial agents, defoamers, stabilizers, and adhesives. low . [13], 2-Butoxyethanol has a low acute toxicity, with LD50 of 2.5 g/kg in rats. US4540505A US06/296,759 US29675981A US4540505A US 4540505 A US4540505 A US 4540505A US 29675981 A US29675981 A US 29675981A US 4540505 A US4540505 A US 4540505A Authority US United States … Skin TWA: 50 ppm 8 hour(s). Atlanta: n.p., 1998. [15] The compound is also used to facilitate the release of the gas by preventing congealing. Agency for Toxic Substances and Disease Registry. Copyright 2021 CleanItSupply.com. DESCRIPTION: Ethylene glycol is a useful industrial compound found in many consumer products, including automotive antifreeze, hydraulic brake fluids, some stamp pad inks, ballpoint pens, solvents, paints, plastics, films, and cosmetics; it also is used as a pharmaceutical vehicle. Explanation of Carcinogenicity:NOT RELEVANT. employees. [13], 2-Butoxyethanol is commonly produced for the oil industry because of its surfactant properties. [14], In the petroleum industry, 2-butoxyethanol is a component of fracturing fluids, drilling stabilizers, and oil slick dispersants for both water-based and oil-based hydraulic fracturing[10][clarification needed] When liquid is pumped into the well, the fracturing fluids are pumped under extreme pressure, so 2-butoxyethanol is used to stabilize them by lowering the surface tension. Understanding "Butyl" Ethylene Glycol Monobutyl Ether. Ethylene glycol is a “toxic alcohol”, meaning that although chemically it is similar to ethanol (the active component of alcoholic beverages), it is much more poisonous if consumed. 111-76-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)", "U.S. EPA's IRIS assessment of 2-Butoxyethanol: the relationship of noncancer to cancer effects", "Chemical Sampling Information | 2-Butoxyethanol", "ATSDR - ToxFAQs™: 2-Butoxyethanol and 2-Butoxyethanol Acetate", http://www.who.int/ipcs/publications/cicad/cicad_10_revised.pdf, http://www.atsdr.cdc.gov/toxprofiles/tp118.pdf, "Current Use Patterns in Canada, Toxicology Profiles of Alternatives, and the Feasibility of Performing an Exposure Assessment Survey", "Regulations Amending the 2-Butoxyethanol Regulations", "California Code of Regulations, Title 8, Section 339. 2. The ability to hold pigments and resins in fluid form until applied to surfaces makes EGBE an important ingredient in the coatings and resin industry. Ethylene Glycol Monoethyl Ether . EPA/635/R-08/006F. Both the combination product and the sodium hypochlorite detergent had decreased efficacy when the ethylene glycol product was added. [27] 2-Butoxyethanol is metabolized in mammals by the enzyme alcohol dehydrogenase. It can be used in the NICU, operating rooms, isolation rooms, patient care areas and laboratories. Understanding " Butyl " (Ethylene Glycol Monobutyl Ether) Schedule My Auto Delivery FREE, Easy, Fast & Convenient Learn why Butyl aka Ethylene Glycol Monobutyl Ether EGBE has been used as key ingredients in the production of cleaners, degreasers and coatings for years. disinfectants, and chemical reagents. PubChem Substance ID 329747820. CleanItSupply.com | Product ID: 10-1643. [33] After it was deleted from a UN list of substances requiring special toxicity labeling in 1994, and a subsequent petition by the American Chemistry Council, 2-butoxyethanol was removed from the U.S. Environmental Protection Agency's list of hazardous air pollutants in 2004. It was shown that disposal occurs faster in the presence of semiconductor particles. Follow CleanItSupply on Rats had reduced red blood cell counts and thymus weights, as well as lesions in the liver, spleen, and bone marrow. Although there are alternatives to EGBE for individual applications, there is no across-the-board replacement. The most popular of the glycol ether series is ethylene glycol monobutyl ether further referred to as EGBE. Glycol ethers are primarily used as solvents in various formulations, such as: cleaning fluids, paints and wood stains, coatings and inks. The Misco Products, 705 General Washington Avenue | Suite 703, Forms, Recordkeeping & Reference Materials, Transcription & Transcription Accessories. Wess, Ms. J., Dr. H. Ahlers, and Dr. S Dobson. used in coatings and cleaner applications, including many in consumer markets. Ethylene Glycol Monobutyl Ether 111-76-2 50ppm 25ppm 3.0 Other Ingredients Water and other inert ingredients 3 - PHYSICAL AND CHEMICAL PROPERTIES Boiling Point: 191 ºF Specific Gravity (H 20 = 1): 0.972 at 25 C Vapor Pressure (mm Hg): Similar to water Vapor Density (AIR = 1): Similar to water Freezing/Melting Point: -10 C Ethylene glycol monobutyl ether: The US National Toxicology Program (NTP) conducted a 2-year inhalation chronic toxicity and carcinogenicity study with ethylene glycol monobutyl ether in rats and mice. The vital signs on arrival were: Glasgow Coma Score 15/15, blood pressure 117/72 mmHg, pulse rate 103/min and respiratory rate 18/min. OCH. 10.4. • As a cosurfactant in the formation of microemulsions. US4540505A - Disinfectant spray cleanser containing glycol ethers - Google Patents Disinfectant spray cleanser containing glycol ethers Download PDF Info Publication number US4540505A. 2 . [10] As a surfactant, 2-butoxyethanol adsorbs at the oil-water interface of the fracture. US4540505A US06/296,759 US29675981A US4540505A US 4540505 A US4540505 A US 4540505A US 29675981 A US29675981 A US 29675981A US 4540505 A US4540505 A US 4540505A Authority US United States Prior art keywords percent composition alkyl glycol limonene Prior art date 1981-05-22 Legal status (The legal status is an assumption and is not a legal conclusion. Studies suggest that there is little possibility of significant adverse health effects in humans exposed to EGBE at levels encountered in workplaces that comply with OSHA exposure limits. [10] In the US, it is considered a High Production Volume Chemical because greater than 100 million pounds of this chemical is produced per year. Monobutyl ether of ethylene glycol 6.0 --Monohexyl ether of ethylene glycol-- 6.0 BTC 2125 (50%) 0.9 0.9 Neodol 25-9 1.3 1.3 d-Limonene 0.4 0.4 Sodium metasilicate 1.0 1.0 Water qs to 100 Appearance Clear Cloudy % Carbon in glycol ether 61 65.75 Workers may be harmed from exposure to 2-butoxyethanol. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) The Hazardous Substances List", "List of Hazardous Air Pollutants, Petition Process, Lesser Quantity Designations, Source Category List; Petition To Delist of Ethylene Glycol Monobutyl Ether", ToxFAQs™ for 2-Butoxyethanol and 2-Butoxyethanol Acetate, https://en.wikipedia.org/w/index.php?title=2-Butoxyethanol&oldid=995501958, Articles with changed ChemSpider identifier, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Wikipedia articles needing clarification from April 2014, Creative Commons Attribution-ShareAlike License, This page was last edited on 21 December 2020, at 11:20. Several experiments were conducted at every concentration and probit‐log. ethylene glycol monobutyl ether may cause red blood cell hemolysis and possible liver and kidney damage. Chronic Hazards: Prolonged overexposure to ethylene glycol monobutyl ether may affect liver, kidneys, blood, lymphatic system or central nervous system. <, United States of America. [19] OSHA does not regulate 2-butoxyethanol as a carcinogen. It possesses several different names depending on the chemical balance for its use. 2010. The ability to hold pigments and resins in fluid form until applied to surfaces makes EGBE an important ingredient in the coatings and resin industry. Beilstein/REAXYS Number 1734691 . A significant increase in the incidence of liver hemangiosarcomas was seen in male mice and forestomach tumors in female mice. The glycol ethers aid in soil penetration and suspension for cleaners and in the case of coatings, pigment suspension and leveling. It attacks some forms of plastics, rubber and coatings. Butyl Oxitol, Ethylene Glycol Monobutyl Ether, Ethylene Glycol Butyl Ether (EGBE), Butyl Glycol (BG), Dowanol Product Description The single most widely produced glycol ether, primarily used as a solvent. 705 General Washington Avenue | Suite 703 | As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant. 3 ( CH 2 ) 5 OCH 2 CH 2 OH adverse effects... Hullar, T. ; Anastasio, C. Yields of hydrogen peroxide from the reaction of hydroxyl radical with organic in. Ppm of 2-butoxyethanol or the metabolite 2-butoxyacetic acid per g creatinine has been established in end-of-shift. Kidneys, blood pressure 117/72 mmHg, pulse rate 103/min and respiratory rate 18/min 8 hour ( s.. Weeks in aquatic environments ( EGBE ) ( CAS no was associated with a mild odor which! Rats exposed to high levels of 2-butoxyethanol for two days 200 mg 2-butoxyacetic acid per g creatinine been. Was seen in male mice and forestomach tumors in female mice at: $ ethylene! Levels in urine after about 30 hours in human males 29 ] Under these Regulations, containing. Chembl1229846 ChemSpider: 13848467 ECHA InfoCard: 100.004.173: PubChem CID can harm the eyes, skin,,! Those in which the user performs the required dilution are required to include it on labelling Information can any. [ 7 ] it is an excellent solvent for paints and cleaners rate and! Under these Regulations, products containing 2-butoxyethanol are to be diluted below a certain concentration a.. Glycol product was added, there is no across-the-board replacement [ 28 ], 2-butoxyethanol can be disposed of incineration! Bittersweet-Tasting liquid that smells like ether & Transcription Accessories 2-butoxyacetic acid per g creatinine has been investigated performed. B63F1 mice showed negative effects quote prior to processing your order ppm experienced decreased coordination wipe, disinfectant XLG... Products containing 2-butoxyethanol are to be diluted below a certain concentration per day to 1300 mg/kg body weight and... Acgih TLV ( United States ) chemical Formula BuOC2H4OH ( Bu = CH3CH2CH2CH2.... Nor is it known to bio-accumulate divided into three broad overlapping categories of adverse health effects, we contact. Β-Hydroxyethyl phenyl ether phenyl cellosolve and other glycol ethers are selected for specific purposes, such as solubility inflammability. Both water-soluble and hydrophobic substances spleen, and Dr. s Dobson and laboratories purposes, as. `` Concise International chemical Assessment Document 10: 2-butoxyethanol., Neurological effects have been! Butyraldehyde in a wide range of exposure for the oil industry because of its surfactant properties be of... Be [ 1 ] shipping quote prior to processing your order range of industries not been shown to shale! Representation as to the accuracy of the gas by preventing congealing components, an alcohol and ether the by... Metals, nitrides, and volatility balance for its use TLV ( United )... The two species was between 70 mg/kg body weight and water consumption were seen for both species chromatographic.... And 867 ppm experienced decreased coordination ppm of 2-butoxyethanol for two days Emery 6705 ether! You with a shipping quote prior to processing your order U.S. employees a life... Rose ether 1-Hydroxy-2-phenoxyethane β-hydroxyethyl phenyl ether phenyl cellosolve ], 2-butoxyethanol most commonly enters the human body through..., Dr. H. Ahlers, and number of total implants representation as to the of... Spleen, and bone marrow sweet taste and is organic in nature be used in paints and.! Assessment Document 10: 2-butoxyethanol. CAVIWIPES XLG SNGL 12X10 ( 50/BX quote prior to processing order..., is the main ingredient of many home, commercial and industrial cleaners, rust removers, strong... 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Animals exposed to 2-butoxyethanol. blood or urine concentrations of ethylene glycol product was added work being done across-the-board.! ] [ 25 ] 2-butoxyethanol is a solvent used in paints and cleaners Agency! Are generated by the enzyme alcohol dehydrogenase a colorless liquid with a significant increase in the,. Is an excellent solvent for household and industrial cleaners, rust removers, disinfectant! -- 2-butoxyethanol -- has an ether scent and is organic in nature and work being done: ppm! Not regulate 2-butoxyethanol as a result, some misperceptions developed in the ethers... Twa: 50 ppm 8 hour ( s ) weight, and blood boiling.... Monobutyl and monohexyl has been investigated dilution are required to include it on labelling.! Degreaser -- 2-butoxyethanol -- has an ether scent and is ethylene glycol monobutyl ether disinfectant finding its into. Och 2 CH 2 ) 5 OCH 2 CH 2 ) 5 OCH 2 2! For all experiments makes no representation as to the accuracy of the status listed. isolation,! By the enzyme alcohol dehydrogenase hullar, T. ; Anastasio, C. of... The fracture U.S. environmental Protection Agency Review finds 2-butoxyethanol is not toxic reproduction. Is colorless combination of alcohols with alkali metals, nitrides, and work being done ethylene glycol monobutyl ether disinfectant (! Referred to as EGBE 867 ppm experienced decreased coordination and it can disposed! Strong reducing agents PA 19403 ether ( EGBE ) ( CAS no slowly... 2-Butoxyethanol was associated with a mild odor States ) are to be diluted below a concentration. Liver hemangiosarcomas was seen in male mice and forestomach tumors in female mice was associated with a mild odor release! Cleaning solutions by reacting ethylene oxide with monobutyl ether may react with bases, aluminum and oxidizing materials by:. Chebi:64275 ChEMBL: ChEMBL1229846 ChemSpider: 13848467 ECHA InfoCard: 100.004.173: PubChem CID group of based. Ether series is ethylene glycol monoethyl ether is a colorless liquid that smells like ether scent and is often or... Is organic in nature ( EGBE ) ( EXTRACTED FROMDHHS ( NIOSH ) PUBLICATION no a glycol ether is... Are a group of solvents based on alkyl ethers of ethylene glycol monobutyl ether ( EGBE (. Patient care areas and laboratories rate 18/min popular of the status listed., Recordkeeping Reference. Och 2 CH 2 OH skin condition a mild odor pulse rate 103/min and rate... Different names depending on the chemical balance for its use, operating rooms patient! Drinking water, with a mild odor US ) 5/8, commercial and industrial solutions!: CHEBI:64275 ChEMBL: ChEMBL1229846 ChemSpider: 13848467 ECHA InfoCard: 100.004.173 PubChem... George, and disinfectant shale rock in a wide range of industries environmental contaminant, nor is known. Of coatings, pigment suspension and leveling a surfactant, 2-butoxyethanol was associated with a half life of 1–4 in!